Title: Factors Influencing Health-Related Quality of Life in Australian People with Pressure Injuries from Chinese Backgrounds: A Qualitative Study Aim: Explore factors influencing health-related quality of life (HRQoL) from the perspectives of people with pressure injuries from Chinese backgrounds, their carers, and healthcare professionals. Methods: Exploratory descriptive. The study was conducted in community settings, underpinned by the pressure injury -specific HRQoL conceptual framework. Data were collected using interviews with people with pressure injuries from Chinese backgrounds, their carers, and healthcare professionals. Thematic analysis techniques were used informed by the framework. Results: Five factors reflected the four domains of the framework underpinned by cultural beliefs and practices: 1) Social support reflected filial piety and family responsibility in daily care, emotional support and pressure injury management. 2) Adherence to treatment reflected reluctance to use analgesics and engage in care. 3) Healthcare professional-patient relationships were built on trust in medical authority, but challenged by language barriers, contributing to frustration and isolation. 5) Health-seeking behaviours highlighted a tendency not to seek professional help, with a preference for self-management. 4) Knowledge and beliefs about pressure injury was found to be limited, as many people underestimated its severity, thereby delaying appropriate care. Conclusions: The findings emphasise the complex factors influencing HRQoL of people with pressure injuries from Chinese backgrounds in Australia. This study highlights the need for person-centred, culturally responsive, and integrated care approaches that support pressure injury management.