Abstract Background: Implementing evidence based support strategies for caregivers of people living with dementia has a significant role in knowledge translation, closing the gap between knowledge and action, stabilising home based care while reducing stress, and improving health related outcomes. There is a need to translate evidence based skill training programs into community care services and to identify the challenges faced for enhancing support for caregivers of people living with dementia. Aim: To synthesise published research studies exploring the facilitators and barriers that influenced the translation of dementia caregiving knowledge into care activities in community care settings. Methods: A mixed method integrative systematic review using a convergent qualitative synthesis approach was applied to this review. Thematic synthesis was used to integrate quantitative and qualitative findings into themes and subthemes. Results: In total, 38 articles were included in this review. Six themes were identified, including: (1) Needs identification; (2) Locally contextualisation; (3) Identifying factors; (4) Tailoring and implementing strategies; (5) Evaluating effectiveness; and (6) Sustaining knowledge utilisation. Conclusion: The facilitators and barriers to translating dementia care knowledge into practice from the perspectives of caregivers, health professionals, and researchers were identified. The findings have significant implications for the development of policy and care services in dementia care. Translating dementia care knowledge into practice needed to be sustainable and meet local contextual needs. Key words Dementia, caregiver, knowledge translation, systematic review